LABOREXPO 2022: Thetis, a new and unique solution for anisotropic nanoparticles characterization

Cordouan Technologies in brief

• VASCO DLS for high concentration and absorbing samples

• WALLIS Zeta potential

• VASCO KIN In situ time resolved DLS

• AMERIGO Standard cell, In situ Time resolved DLS & Zeta potential

• THETIS Continuous Multi angle Time resolved DLS, SLS and DDLS

Why Nanoparticles size matters?

• Related to the specific surface of the particles

• Ability to penetrate membranes or interact with surface

• Functionalization and self assembly capabilities

• Optical, mechanical and electrical properties

• Etc

Pragolab: Why Nanoparticles size matters

Brownian motion: a signature of NP size

Brownian motion:=Random walk

Pragolab: Brownian motion a signature of NP size

DL measurement Principle (1.)

Measure light scattering fluctuation to probe the Brownian motion of NPs

Pragolab: DL measurement Principle

DL measurement Principle (2.)

Brownian motion - Translational Diffusion coefficient- Hydrodynamic diameter

Pragolab: DL measurement Principle 2

Correlogram and Data Processing

• Inversion problem: How to find the optimum exponential curve fitting the experimental correlogram?

• Inversion algorithms for NP size analysis

Pragolab: Correlogram and Data Processing

Algorithm / Number of populations / Distribution / Model

• Cumulants / Monomodal Continuous / Yes

• Pade Laplace / Multi modal discrete / No

• SBL / Multimodal continuous / Yes

(SBL is Space Basel Learning)

Pragolab: Inversion algorithms for NP size analysis

Pragolab: DL Measurement

Why Nanoparticles shape matters?

1. Advanced materials needs more sophisticated NPs

2. Graphene, Carbon nanotube, Silver nanotube are the next generation electrical transmitters

3. New shapes for NPs available now

Pragolab: Why Nanoparticles shape matters

Examples of anisotropic NPs

Hybrid nanomaterials:

• Combination of various material properties into one

• Rise of new properties,

• Examples:

  • Efficient solar cell materials
  • New optical materials
  • Nanocrystals for structural improvement
  • Magnetic NPs for imaging

Behaviour anisotropic particles

Pragolab: Behavior anisotropic particles

Anisotropic Diffusion Coefficients

• Calculation can be performed

• L, w and L/w can be obtained

Pragolab: Anisotropic Diffusion Coefficients

D-DLC Principle

• Step 1: Detecting intensity on VV

• Step 2: Detecting intensity on VH

Pragolab: D-DLS Principle

Pragolab: D-DLS Principle

Pragolab: Analytical method

Pragolab: Analytical method

THETIS: A multi-angle DLS, SLS and D-DLC

• DLS, D-DLS and SLS in one instrument

• Multi-angle scattering measurement system: from 30° to 160°

• Real time and Time resolved Software correlator

• High Power single mode laser λ=635 nm

• Scattered Intensity measurements on 2 perpendicular polarizations

• Temperature controlled from 1°C to 70 °C

• Molecular weight, concentration and replay modes for DLS and DDLS data

• 3 different algorithms for particle size measurements

ProTheta Software

Pragolab: ProTheta software

Advanced functionalities and intuitive menus

Points:

1. Both VV and VH correlogram

2. 2 Channels (VV, VH) Time resolved D-DLS

3. User selected/automatic scattering angle setting

4. Automatic calculation of length, width & Aspect ratio / Rotational & Translational Diffusion Coefficient measurements

LABOREXPO 2022: Advanced functionalities and intuitive menus

Experimental results on nanorods

Pragolab: Experimental results on nanorods

Pragolab: Experimental results on nanorods