Modelisation and Real-Time monitoring of Glycosylation during mAb manufacturing process using Raman Spectroscopy

In this webinar, you will learn:

• How Raman spectroscopy will enhance your process monitoring capacities integrating high end CQAs (glycans)
• How to assess model quality: accuracy and robustness
• How to perform Raman measurment regardless of lab light environment

Detailed description:

This webinar presents a unique opportunity to delve into the convergence of cutting-edge technology and bioprocessing. Here, Raman spectroscopy stands out as a game-changer, unveiling the intricacies of glycosylation patterns in real time—an essential element in the manufacturing of monoclonal antibodies.

The use case highlighted in this webinar illustrates a methodology for building robust and proven glycan models, enabling real-time monitoring of the glycosylation profile. It opens new doors for tailoring and optimizing glycosylation patterns throughout the monoclonal antibody manufacturing process.

Presenter: Jérémy Peyrol (USP Innovation Expert - BioVV innovation for biologics)

Jérémy Peyrol, MSc in Biotechnology, joined Merck KGaA, Darmstadt, Germany in 2013 as an Upstream Development Scientist. Since then, he has been working on various projects including high-throughput process development on bacteria and yeast, and has served as Project leader on mAb and other complex protein expression systems.

In his current role, Jérémy is an Upstream Innovation Expert within our Life Science Services CTDMO business, and focuses on testing and developing next generation solutions for cell line development, upstream processes, and process analytical technologies.