Tým vedený vědci z CEITEC Masarykovy univerzity objasnil mechanismus infekce u bičíkatých bakteriofágů, tedy jedné ze skupin virů, které napadají bakterie. Tyto fágy cílí mimo jiné na zlatého stafylokoka (Staphylococcus aureus), významného původce infekcí často odolného vůči antibiotikům, který patří mezi bakterie vyznačující se mimořádně silnou buněčnou stěnou. Přestože byl mechanismus infekce u některých jiných bakteriofágů popsán již dříve, u bičíkatých fágů napadajících stafylokoka a další bakterie se silnou buněčnou stěnou zůstával dosud neznámý. Vědci nyní ukázali, jak bakteriofág dokáže prorazit ochrannou vrstvu bakteriální buňky a dopravit do ní svou genetickou informaci. Výsledky výzkumu tak mohou přispět k vývoji nových přístupů v boji proti bakteriím odolným vůči antibiotikům.Zlatý stafylokok (Staphylococcus aureus) patří mezi nejčastější původce infekcí u lidí. Může způsobovat kožní infekce, zápaly plic i život ohrožující otravy krve. Řada jeho kmenů je navíc rezistentní vůči běžně používaným antibiotikům, což zvyšuje zájem o alternativní způsoby léčby, mezi které patří právě bakteriofágy.„Bakteriofágy jsou nejpočetnější biologické entity na Zemi a bakterie napadají už miliardy let. Přesto stále neznáme detaily toho, jak přesně dokážou překonat buněčnou stěnu některých Gram-pozitivních (tlustostěnných) bakterií. Nyní jsme mohli tento proces zrekonstruovat díky snímkům bakteriofága před a po přichycení na bakterii“ říká <a target="_blank" rel="noopener noreferrer" href="https://www.ceitec.cz/mgr-jan-binovsky-ph-d/u91173?page=publication">Ján Bíňovský</a> z CEITEC Masarykovy univerzity (MUNI), který výzkum vedl spolu s&nbsp;Martou Šiborovou.Studovaný bakteriofág 812 napadá právě bakterii Staphylococcus aureus. Vědci zjistili, že po rozpoznání správného hostitele u něj dochází k rozsáhlým změnám v&nbsp;proteinové struktuře na konci bičíku. Jednotlivé části této struktury připomínající přistávací modul se přeskupí do nové podoby, která umožní pevné přichycení viru k povrchu bakterie. Zároveň se aktivuje mechanismus, který spustí smrštění bičíku viru.<img src="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/CEITEC_Jak_zabit_zlateho_stafylokoka_novy_pohled_na_viry_ktere_si_poradi_s_bakteriemi_01c86d5e42.jpg" alt="CEITEC/Plevka Lab: Jak zabít zlatého stafylokoka: nový pohled na viry, které si poradí s bakteriemi: Fág před přichycením na buňku." srcset="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/thumbnail_CEITEC_Jak_zabit_zlateho_stafylokoka_novy_pohled_na_viry_ktere_si_poradi_s_bakteriemi_01c86d5e42.jpg 245w," sizes="100vw" width="4339" height="1600"><img src="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/CEITEC_Jak_zabit_zlateho_stafylokoka_novy_pohled_na_viry_ktere_si_poradi_s_bakteriemi_2_53422574db.jpg" alt="CEITEC/Plevka Lab: Jak zabít zlatého stafylokoka: nový pohled na viry, které si poradí s bakteriemi: Stav fágu po přichycení na buňku." srcset="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/thumbnail_CEITEC_Jak_zabit_zlateho_stafylokoka_novy_pohled_na_viry_ktere_si_poradi_s_bakteriemi_2_53422574db.jpg 245w," sizes="100vw" width="4085" height="1600">„Tento proces funguje podobně jako uvolnění natažené pružiny. Bičík bakteriofága se zkrátí přibližně na polovinu své původní délky a uvolněná energie protlačí centrální trubici skrz ochranné vrstvy bakterie. Následně může virus dopravit svou genetickou informaci do jejího nitra a zahájit infekci,“ vysvětluje Marta Šiborová.Na rozdíl od mnoha jiných bakterií je buněčná stěna zlatého stafylokoka mimořádně silná. Vědci proto zkoumali v detailu, jak si s touto překážkou bakteriofág poradí. Zjistili, že virus využívá kombinaci mechanické síly a enzymů. Některé části jeho infekčního aparátu pravděpodobně narušují teichoové kyseliny tvořící vnější ochrannou vrstvu buněčné stěny. Další proteiny následně rozkládají peptidoglykan, tedy hlavní stavební materiál bakteriální stěny. Nakonec bakteriofág prorazí i vnitřní lipidovou membránu. Teprve poté dojde k průniku infekční trubice do buňky.Výsledky ukazují, že bakteriofág nefunguje jako jednoduchá „jehla“, ale jako složitý nanostroj složený z desítek spolupracujících proteinů.Přestože jde o základní výzkum, získané poznatky mohou být důležité i pro budoucí medicínské aplikace. Bakteriofágy jsou považovány za jednu z možných cest léčby infekcí způsobených bakteriemi odolnými vůči antibiotikům. „Pokud chceme bakteriofágy v budoucnu cíleně využívat nebo dokonce upravovat pro léčebné účely, musíme nejprve detailně porozumět tomu, jak fungují. Naše práce poskytuje znalosti, jak bakteriofágy rozpoznávají své hostitele a jak zahajují infekci,“ říká <a target="_blank" rel="noopener noreferrer" href="https://www.ceitec.cz/doc-mgr-pavel-plevka-ph-d/u26854">Pavel Plevka</a>, strukturní biolog a vedoucí výzkumné skupiny na CEITEC MUNI.<blockquote>Na studii, která byla publikována v&nbsp;<a target="_blank" rel="noopener noreferrer" href="https://link.springer.com/article/10.1038/s44318-026-00834-9">EMBO Journal</a>, spolupracovali i vědci a vědkyně z&nbsp;Přírodovědecké fakulty Masarykovy univerzity.</blockquote><img src="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/CEITEC_Jak_zabit_zlateho_stafylokoka_novy_pohled_na_viry_ktere_si_poradi_s_bakteriemi_3_fba5a65145.jpg" alt="CEITEC/Plevka Lab: Jak zabít zlatého stafylokoka: nový pohled na viry, které si poradí s bakteriemi: Černá = proteinová struktura na konci bičíku po změně struktury (přichycení k povrchu bakteriální stěny), červená = část bičíku, která se začíná smršťovat (zvětšení tloušťky bičíku), modrá = část bičíku, která je ještě napnutá (původní tloušťka bičíku)." srcset="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/thumbnail_CEITEC_Jak_zabit_zlateho_stafylokoka_novy_pohled_na_viry_ktere_si_poradi_s_bakteriemi_3_fba5a65145.jpg 245w," sizes="100vw" width="1600" height="782"><blockquote><h4>Původní článek</h4><h4><a target="_blank" rel="noopener noreferrer" href="https://link.springer.com/article/10.1038/s44318-026-00834-9">Conformational changes of the baseplate regulating tail contraction of Staphylococcus phage 812</a></h4>Ján Bíňovský, Marta Šiborová, Maryna Zlatohurska, Jiří Nováček, Pavol Bárdy, Roman Baška, Karel Škubník, Tibor Botka, Martin Benešík, Roman Pantuček, Konstantinos Tripsianes &amp; Pavel PlevkaEMBO J (2026)<a target="_blank" rel="noopener noreferrer" href="https://doi.org/10.1038/s44318-026-00834-9">https://doi.org/10.1038/s44318-026-00834-9</a>&nbsp;<h6>licencováno pod <a target="_blank" rel="noopener noreferrer" href="https://creativecommons.org/licenses/by/4.0/">CC-BY 4.0</a></h6></blockquote>

Jak zabít zlatého stafylokoka: nový pohled na viry, které si poradí s bakteriemi

Čistírny odpadních vod každý den bojují s látkami, které z vody jen tak nezmizí. Odbourávání dusíkatých látek je na čistírnách velmi důležité. Když jich ve vodě zůstane moc, škodí řekám i životu v nich. Karel Havlíček z CXI TUL byl spoluřešitelem projektu HYMNA, který spojil dvě známé technologie čištění do jednoho systému. A přidal k nim něco, co se na čistírnách běžně nepoužívá: nanovlákna.Celý název projektu zní Hybridní systém MBR-MBBR využívající nanomateriály pro dočišťování odpadních vod. Zkratka je HYMNA. „Zní to trochu vznešeně,“ směje se spoluřešitel Karel Havlíček z&nbsp;Oddělení technologie ochrany životního prostředí. Ale cíl vznešený byl. Voda, která z čistírny odtéká, není vždy tak čistá, jak by mohla být. A to je problém, který stojí za řešení.<h4>Síto a kuličky</h4>Za zkratkami MBR a MBBR se skrývají dvě technologie, které čistírny obvykle nasazují každou zvlášť. Karel je ale poslal do jedné linky za sebou a ukázal, že společně dokážou fungovat výrazně lépe. Kombinaci ověřil v praxi a navrhl z ní technologii, která má jasný postup, měřitelné výsledky a potenciál pro reálné nasazení.MBR funguje jako jemné síto. Membrány zachytí nečistoty, organické látky i nerozpuštěné částice. Jenže ani tak není hotovo, v čiré vodě pořád zůstávají dusíkaté látky.Na ně Karel Havlíček spolu s partnery nasadil druhou část technologie: MBBR. Malé plastové kuličky s otvory a nanovlákny uvnitř se za pomoci vzdušnění volně pohybují v nádrži. Na povrchu nanovláken rostou a žijí mikroorganismy, které přeměňují amoniakální dusík na dusičnany.Proč na tom záleží? Amoniakální dusík je pro ryby jedovatý, poškozuje jim žábry a ve vyšších koncentracích je zabíjí. Přebytek dusíku spouští přemnožení řas, takže voda zelená, ubývá v ní kyslíku a život v ní se dusí.<img src="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/CXI_TUL_Kulicky_s_nanovlakennym_srdcem_Takhle_se_da_cistit_voda_lip_2_6559ff2373.jpg" alt="CXI TUL: Kuličky s nanovlákenným srdcem. Takhle se dá čistit voda líp." srcset="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/thumbnail_CXI_TUL_Kulicky_s_nanovlakennym_srdcem_Takhle_se_da_cistit_voda_lip_2_6559ff2373.jpg 117w," sizes="100vw" width="768" height="1024"><h4>Kuličky s nanovlákenným srdcem</h4>Kuličky nejsou náhoda. Karel vložil do plastových tělísek s otvory nanovlákenné nosiče, což je jemný vláknitý materiál, na kterém se mikroorganismy rychle a pevně uchytí. Navrhoval je už v dizertační práci.Cesta k finální podobě nebyla přímá. Původně šlo o nanovlákennou vrstvu. Ta ale z kuliček postupně utíkala. Nahradili ji přízí, která drží. Výsledkem je užitný vzor pro nové nosiče biomasy.Hlavní výhoda je rychlost uchycení. Na klasických materiálech trvá osídlení mnohem déle. Na nanovláknech se mikroorganismy nastěhují rychle. To je klíčové zvlášť tam, kde je voda pro ně nepříznivá nebo toxická.Průmyslové odpadní vody bývají tak znečištěné, že bakterie na běžných nosičích nepřežijí. Na nanovlákenném povrchu se ale stihnou uchytit dřív, než je prostředí zničí. Systém pak funguje i tam, kde by jiné technologie selhaly.<img src="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/CXI_TUL_Kulicky_s_nanovlakennym_srdcem_Takhle_se_da_cistit_voda_lip_3_290e60625f.jpg" alt="CXI TUL: Kuličky s nanovlákenným srdcem. Takhle se dá čistit voda líp." srcset="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/thumbnail_CXI_TUL_Kulicky_s_nanovlakennym_srdcem_Takhle_se_da_cistit_voda_lip_3_290e60625f.jpg 117w," sizes="100vw" width="768" height="1024"><h4>Číslo, které překvapilo</h4>Nejdůležitější bylo, jak si systém poradí s&nbsp;amoniakálním dusíkem. Tým zkoušel i extrémní koncentrace až osmdesát miligramů na litr. A to už není dolaďování. To je zátěžová zkouška na hraně. Taková, která může ochromit nebo úplně zastavit život čisticích mikroorganismů.Systém ji zvládl. Na odtoku naměřili pod jeden miligram na litr.„Dostali jsme se na číslo, které často nezvládne ani běžná čistírna,“ shrnul svoje překvapení Karel.<img src="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/CXI_TUL_Kulicky_s_nanovlakennym_srdcem_Takhle_se_da_cistit_voda_lip_4_00a10f7915.jpg" alt="CXI TUL: Kuličky s nanovlákenným srdcem. Takhle se dá čistit voda líp." srcset="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/thumbnail_CXI_TUL_Kulicky_s_nanovlakennym_srdcem_Takhle_se_da_cistit_voda_lip_4_00a10f7915.jpg 117w," sizes="100vw" width="768" height="1024"><h4>Čistírna v kontejneru</h4>Spojení obou technologií přineslo něco navíc. Systém může fungovat nejen jako doplněk (post-treatment) za běžnou čistírnou, ale i jako samostatná modulární čistírna. Žádná stavba, systém lze přivézt, zapojit a spustit.„To ocení hlavně průmyslové provozy. Firmy, které dnes znečištěnou vodu odvážejí v barelech jako nebezpečný odpad, by mohly část čištění zvládnout samy,“ vysvětluje Karel. Pro firmy by to podle něj znamenalo méně odpadu, méně logistiky a nižší náklady.<img src="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/CXI_TUL_Kulicky_s_nanovlakennym_srdcem_Takhle_se_da_cistit_voda_lip_5_15c7bfefc3.jpg" alt="CXI TUL: Kuličky s nanovlákenným srdcem. Takhle se dá čistit voda líp." srcset="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/thumbnail_CXI_TUL_Kulicky_s_nanovlakennym_srdcem_Takhle_se_da_cistit_voda_lip_5_15c7bfefc3.jpg 117w," sizes="100vw" width="768" height="1024"><h4>Mýtus, který nevyšel</h4>Mimo hlavní projekt si Karlův tým položil ještě jednu otázku: dokáží mikroorganismy v&nbsp;běžném čistírenském biofilmu na nosičích rozkládat mikropolutanty? Tedy zbytky léků nebo pesticidů, které se dostávají do vody?Některé studie naznačovaly, že by to možné být mohlo.Nadšení ale rychle opadlo. „K žádnému rozkladu nedochází. Mikropolutanty se v systému jen hromadí,“ konstatuje Karel. Zachytí je, ale nezničí. Na to jsou potřeba silnější metody jako třeba ozon nebo UV záření.<img src="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/CXI_TUL_Kulicky_s_nanovlakennym_srdcem_Takhle_se_da_cistit_voda_lip_f8251f3b2e.jpg" alt="CXI TUL: Kuličky s nanovlákenným srdcem. Takhle se dá čistit voda líp." srcset="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/thumbnail_CXI_TUL_Kulicky_s_nanovlakennym_srdcem_Takhle_se_da_cistit_voda_lip_f8251f3b2e.jpg 110w," sizes="100vw" width="724" height="1024">Projekt HYMNA v programu TREND Technologické agentury ČR ve spolupráci se společností ENVI-PUR, s.r.o. (hlavní řešitel) a Pražské vodovody a kanalizace, a.s.

Kuličky s nanovlákenným srdcem. Takhle se dá čistit voda líp.

<h3>Měřte chytřeji s menší spotřebou rozpouštědel</h3><h4>Malé objemy. Maximální flexibilita.</h4>Představujeme novou jednotku Small Flow Dispersion Unit pro systémy <a target="_blank" rel="noopener noreferrer" href="https://icpms.cz/products/1806">Litesizer DIF</a> a <a target="_blank" rel="noopener noreferrer" href="https://icpms.cz/products/1366">Litesizer DIA</a>, která rozšiřuje možnosti měření a zároveň výrazně snižuje spotřebu rozpouštědel.<img src="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/Anton_Paar_Litesizer_a_small_flow_dispersion_unit_2_33f4e216f7.jpg" alt="Anton Paar: dispergační jednotky Small Flow pro analyzátory Litesizer DIA a DIF" srcset="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/thumbnail_Anton_Paar_Litesizer_a_small_flow_dispersion_unit_2_33f4e216f7.jpg 234w," sizes="100vw" width="2400" height="1600">Je ideální pro aplikace využívající omezená, drahá, toxická nebo korozivní rozpouštědla. Automatické plnění minimalizuje kontakt obsluhy se vzorkem, zatímco ultrazvuková sonikace zajišťuje spolehlivou dispergaci částic a přesné výsledky analýzy.Volitelný zobrazovací modul navíc umožňuje analyzovat tvarové parametry částic a získat ještě podrobnější charakterizaci vzorků.<blockquote><a target="_blank" rel="noopener noreferrer" href="https://icpms.cz/products/2484">Více o Smart Flow Dispersion Unit ZDE</a></blockquote><blockquote>Pro více informací nás kontaktujte<ul><li>CZ: Ing. Jiří Špringer (jiri.springer@anton-paar.com)</li><li>SK: Mgr. Richard Landl (richard.landl@anton-paar.com)</li></ul></blockquote>

Novinka Small Flow Dispersion Unit v nabídce Anton Paar

Životní prostředí

Vody

Věda a výzkum

Video

Článek

Produkt

Je výzkumné centrum zaměřené na oblast živých věd, pokročilých materiálů a technologií.  Vznikl v roce 2011 na základech šesti významných brněnských univerzit a výzkumných institucí. Od doby jeho nedávného vzniku se daří budovat významné vědecké centrum, a již nyní se řadí mezi špičkové evropské instituce.

CEITEC

Ústav pro nanomateriály, pokročilé technologie a inovace Technické univerzity v Liberci, známý také jako CXI TUL, byl založen v roce 2009. Naším posláním je podporovat dlouhodobou vizi TUL v oblasti spolupráce s průmyslem a vytváření inovací.

CXI TUL

Anton Paar vyvíjí, vyrábí a distribuuje vysoce přesné laboratorní přístroje a procesní měřicí systémy a nabízí uživatelsky specifická řešení automatizace a robotizace.

Anton Paar

Agilent Technologies

Thermo Fisher Scientific

SciY/Mestrelab Research

<div><h4>Unlock the Power of Full-Spectrum Flow Cytometry</h4>A two-part masterclass designed to help you understand, design, and apply high-dimensional flow cytometry workflows across immunology, oncology, and vaccine research.<h5>Session 2: Designing and Analysis of Spectral Flow Experiments</h5><ul><li>Key Advantages of Spectral Technology. Learn how spectral systems enable higher multiplexing, improved resolution, and enhanced flexibility in panel design for complex experiments.</li><li>Workflow of Spectral Flow Cytometry. Step through the complete experimental journey—from panel design and sample preparation to acquisition and interpretation of high-dimensional data.</li><li>Unmixing and Data Analysis Strategies. Gain insights into spectral unmixing principles and advanced analytical approaches that transform raw data into meaningful biological interpretation.</li></ul><h5>Why Attend?</h5><ul><li>Move beyond conventional flow limitations</li><li>Design high-dimensional experiments confidently</li><li>Learn real-world applications</li><li>Interact with flow cytometry experts</li></ul><blockquote>Presenter: Dr. Hemant Agrawal (Director, Flowcytometry Solutions Pvt. Ltd., India)Flow cytometry educationalist and global trainer with 15+ years of experience. Conducted 80+ onsite and 40+ online workshops worldwide. An active member of ISAC (International Society for Advancement of Cytometry) task forces, Dr. Agrawal is widely recognized for advancing cytometry education globally and has been an invited faculty at prestigious Indo-US Cytometry Workshops.</blockquote><blockquote>Presenter: Dr. Saket Siddharth (Field Application Scientist – Flowcytometry, Agilent Technologies)Saket Siddharth is a Flow Cytometry and Cell Analysis specialist with over nine years of experience spanning clinical cytometry, spectral cell sorting, and advanced multicolor panel design. He holds a Ph.D. from the Helmholtz Centre for Infection Research, Brunswick, Germany, and has developed strong expertise across antibody development, high-throughput screening, and assay validation for translational and research applications.</blockquote></div>

Agilent Technologies: Spectral Flow Cytometry Masterclass - Session 2

Spectral Flow Cytometry Masterclass - Session 2

Learn high-dimensional spectral flow cytometry workflows with Cytek. Master panel design, sample prep, and advanced spectral unmixing strategies

Spectral Flow Cytometry Masterclass

As materials become increasingly sophisticated, understanding their optical properties is essential for driving innovation, improving product performance, and ensuring quality. Whether developing anti-reflective coatings, optimising solar cell efficiency, designing specialty glass, or researching next-generation materials, accurate optical characterisation is a critical part of the workflow.Join us for this webinar to discover how the Agilent UV-Vis-NIR spectrophotometer enables researchers and industry professionals to measure and characterise a broad range of optical properties across diverse sample types and applications.The webinar will showcase measurement techniques for transmission, reflectance, diffuse reflectance, and angular measurements, highlighting how the Agilent UV-Vis-NIR platform delivers reliable and reproducible data for both research and industrial applications.<h4>Why Attend?</h4>In this session, you will learn:<ul><li>How the Agilent UV-Vis-NIR can be used to characterise thin films, coatings, solar materials, and glass.</li><li>Techniques for measuring transmission, reflectance, and diffuse reflectance with confidence.</li><li>Methods for determining film thickness and evaluating optical performance.</li><li>How specialised accessories expand measurement capabilities for challenging samples.</li><li>Best practices for obtaining accurate, reproducible results across a variety of applications.</li><li>Real-world examples demonstrating how optical measurements can accelerate research and product development.</li></ul><h4>Who Should Attend?</h4>This webinar is designed for:<ul><li>Academic Researchers and Students<ul><li>Researchers in materials science, physics, chemistry, and engineering.</li><li>Scientists investigating thin films, nanomaterials, optical materials, and photonic devices.</li><li>Graduate students and postdoctoral researchers seeking advanced optical characterisation techniques.</li></ul></li><li>Solar and Photovoltaics<ul><li>Scientists and engineers developing solar cells and photovoltaic materials.</li><li>Researchers evaluating anti-reflective coatings and light management strategies.</li><li>Teams working to improve solar cell efficiency through optical optimisation.</li></ul></li><li>Glass and Coatings Industries<ul><li>Manufacturers of architectural, automotive, and specialty glass.</li><li>Researchers developing low-emissivity and anti-reflective coatings.</li><li>Quality control and R&amp;D professionals responsible for optical performance testing.</li></ul></li><li>Advanced Materials and Industrial R&amp;D<ul><li>Thin film and semiconductor researchers.</li><li>Optical coating manufacturers.</li><li>Scientists working with displays, sensors, filters, and advanced functional materials.</li><li>Analytical laboratories requiring precise optical characterisation.</li></ul></li></ul><h5>Featured Applications</h5><ul><li>Thin film and multilayer coating analysis</li><li>Anti-reflective and optical coating characterisation</li><li>Solar cell and photovoltaic material evaluation</li><li>Optical filter transmission and blocking measurements</li><li>Architectural and specialty glass analysis</li><li>Reflectance measurements at varying angles of incidence</li><li>Film thickness determination</li><li>Diffuse reflectance measurements of scattering materials</li><li>Optical characterisation of emerging materials in academia and industry</li></ul>Discover how the Agilent UV-Vis-NIR platform combines exceptional optical performance, flexible sampling accessories, and intuitive workflows to provide the insights needed to advance research, optimise products, and solve challenging analytical problems.<blockquote>Presenter: Mr. Rajwar Chandra (Product Specialist - Spectroscopy, Agilent Technologies)Chandra Rajwar is a Product &amp; Market Specialist with over 20 years of experience in Molecular Spectroscopy products and analytical instrumentation. He specializes in UV-Vis, FTIR, Raman, and related spectroscopy solutions, supporting customers with application development, workflow optimization, and analytical excellence across pharmaceutical, chemical, environmental, and research industries.</blockquote><blockquote>Presenter: Ms. Vijaya Jyothi (Product Specialist - Spectroscopy, Agilent Technologies India Pvt. Ltd.)Vijaya Jyothi is a seasoned product specialist at Agilent Technologies. She manages the spectroscopy division, having extensive expertise in spectroscopy applications across diverse industries, offering deep insights and solutions tailored to varied analytical needs.</blockquote>

Agilent Technologies: Characterising Advanced Materials with the Agilent UV-Vis-NIR - From Thin Films and Solar Cells to Glass and Optical Coatings

Characterising Advanced Materials with the Agilent UV-Vis-NIR: From Thin Films and Solar Cells to Glass and Optical Coatings

Characterize thin films, solar cells, and coatings with Agilent UV-Vis-NIR. Master reflectance, transmission, and angular measurement workflows

Materials Characterization with Agilent UV-Vis-NIR

<h4>Atomic Webinar Series</h4>Ensuring food safety requires accurate detection of toxic elements at very low concentration levels, as mandated by international standards such as AOAC Official Method 2015.01. Food matrices pose significant analytical challenges because of their complex compositions, high dissolved solids after digestion, and spectral interferences, including polyatomic and doubly charged rare-earth element species. Simultaneously, food testing laboratories need high sample throughput and minimal operator intervention. This study presents an automated ICP-MS/MS workflow for multi-element analysis of various food matrices using discrete sampling and intelligent autodilution.<blockquote>Presenter: Jeff Sayen (ICP-MS Application Scientist, Agilent Technologies)Jeffrey Sayen s an ICP-MS Application Scientist at Agilent Technologies with over 15 years of experience in analytical chemistry. He specializes in atomic spectroscopy techniques, including ICP-MS, ICP-OES, and Flame AA. Jeffrey is passionate about ICP-MS and enjoys delivering product and application overviews at customer sites, seminars, and industry events. Prior to joining Agilent, he held the position of Senior Field Application Scientist at another major instrument manufacturer, where he focused on analytical methodologies across a range of regulated industries. He holds both undergraduate and graduate degrees in Inorganic Chemistry from Michigan State University.</blockquote>

Agilent Technologies: Atomic Spectroscopy Webinar Series - Elemental Analysis of Foods by Agilent 9500 ICP-QQQ with an Autodilutor

Elemental Analysis of Foods by Agilent 9500 ICP-QQQ with an Autodilutor

Optimize food analysis with the Agilent 9500 ICP-QQQ. Learn how intelligent autodilution resolves interferences and boosts laboratory throughput

Food Elemental Analysis with Agilent 9500 ICP-QQQ

This webinar provides an overview of the Advanced Dilution System (ADS 2), including its operating principles and key parameters for optimization. Troubleshooting approaches will be discussed, with an emphasis on resolving timing, carryover, and precision-related challenges.<blockquote>Presenter: Ana García González (Atomic Spectroscopy Application Scientist, Agilent Technologies)Ana Garcia is the Atomic Spectroscopy Application Scientist at Agilent Technologies. Ana has a broad background in atomic spectroscopy technologies, including international experience developing and validating analytical spectroscopy methods for the geochemical industry. She has also published in the fields of molecular spectroscopy and chemometrics. Ana holds a MSc in plant Biotechnology at CINVESTAV, México, and a Bachelor of Science in Biotechnology Engineering.</blockquote>

Agilent Technologies: Optimizing ADS 2 Autodilutor

Optimizing ADS 2 Autodilutor: Operation, Troubleshooting, & Best Practices

Master the Agilent ADS 2 autodilutor. Learn troubleshooting strategies for timing, carryover, and precision challenges to optimize your workflow

Optimizing the ADS 2 Autodilutor: Troubleshooting

Environmental laboratories face increasing pressure to boost sample throughput while maintaining high data quality across various matrices, including natural waters, soils, and sediments. These samples often have high levels of dissolved solids and complex interference profiles, making fast and reliable multi-element analysis difficult with traditional ICP-MS methods. This work describes a high-throughput ICP-MS/MS workflow for routine environmental analysis that combines discrete sampling with advanced interference control using a single helium mode.&nbsp;<blockquote>Presenter: Yan Cheung, PhD (Application Scientist, Agilent Technologies, Inc.)Yan received her Ph.D. in Analytical Chemistry from Indiana University Bloomington. She joined Agilent Technologies as an Application Scientist in the Life Science and Chemical Analysis team in April 2020. Yan has extensive experience in operating and method development in ICP-MS. Yan also has years of experience working in the oil and gas industry.</blockquote>

Agilent Technologies: Analysis of Environmental Waters by 9500 ICP-QQQ in Advanced Helium Mode

Analysis of Environmental Waters by 9500 ICP-QQQ in Advanced Helium Mode

Boost environmental lab throughput with the Agilent 9500 ICP-QQQ. Learn how advanced helium mode resolves interferences in complex matrices

Environmental Analysis via 9500 ICP-QQQ Helium Mode

Understanding the chemical stability of MXenes under realistic operating conditions is essential for their reliable use in ion separation and electrochemical systems.&nbsp;In this webinar, we highlight the application of inductively coupled plasma optical emission spectroscopy (ICP-OES, Agilent-5900) as a powerful analytical tool to quantitatively evaluate elemental evolution during MXene degradation.&nbsp;By tracking dissolved species in the solution, ICP-OES enables precise assessment of metal leaching and oxidation under pH and temperature control. Furthermore, we investigate the ion selectivity of Ti₃C₂Tₓ MXene channels and their underlying physicochemical origins. We demonstrate that the interlayer spacing and surface chemistry critically regulate ion mobility, leading to pronounced Li+ selectivity among monovalent and multivalent ions. In these studies, ICP-OES 5900 serves as an indispensable analytical platform, helping us establish a fundamental basis for the application of MXenes in ion separation technologies.<blockquote>Presenter: Yuan Zhang (Research Assistant Professor, Drexel Nanomaterials Institute, Drexel University)Dr. Yuan Zhang is a Research Assistant Professor at the Drexel Nanomaterials Institute, Drexel University. An Alexander von Humboldt Fellow and a Cotswold Postdoctoral Fellow, she earned her Ph.D. in Leibniz Institute for New Materials in Germany. Her expertise spans materials science and electrochemistry, focusing on molecular-scale ion transport, 2D MXene nanofluid, and energy storage.</blockquote>

Agilent Technologies: Elemental Evaluation of MXene Degradation and Application in Ion Separation

Elemental Evaluation of MXene Degradation and Application in Ion Separation

Study MXene stability and ion separation with Agilent. Learn how the 5900 ICP-OES tracks degradation, oxidation, and lithium selectivity

Evaluating MXene Degradation & Ion Separation via ICP-OES

Diffuse reflectance infrared Fourier transform spectroscopy (DRIFTS) is a powerful technique for investigating catalyst surface chemistry under reaction conditions. In this live webinar, subject matter specialists from Michigan State University, Specac, and Thermo Fisher Scientific will discuss how in situ DRIFTS can be used to study dry reforming of methane over ceria-supported catalysts and provide insight into the surface species and reaction intermediates involved in catalytic CO₂ utilization.The session will explore DRIFTS experimental setup considerations, approaches for relating spectral observations to catalyst behavior, and examples of how researchers use in situ spectroscopy to investigate CO₂ activation and metal-support interactions. Presenters will also discuss complementary characterization techniques, including CO-DRIFTS, CO₂-DRIFTS, and CO₂-TPD-DRIFTS, and their role in catalyst research workflows.Attendees will be able to gain practical knowledge that can help strengthen catalyst characterization strategies, support experimental design, and improve interpretation of catalyst behavior in heterogeneous catalysis research.<h4>Key takeaways</h4>By attending this webinar, you can learn several aspects about this specific method of analysis:<ul><li>Apply in situ DRIFTS to investigate catalyst surface chemistry under reaction conditions</li><li>Monitor adsorbed species and reaction intermediates during dry reforming of methane</li><li>Relate spectral observations to catalyst behavior and reaction mechanisms</li><li>Investigate CO₂ activation and metal-support interactions in ceria-supported catalyst systems</li><li>Evaluate when to use complementary techniques such as CO-DRIFTS, CO₂-DRIFTS, and CO₂-TPD-DRIFTS</li><li>Incorporate DRIFTS into catalyst characterization workflows to support more informed research and development decisions.</li></ul><h4>Who should attend</h4><ul><li>Catalysis researchers</li><li>Materials scientists</li><li>Surface scientists</li><li>FTIR and vibrational spectroscopy users</li><li>Academic researchers studying heterogeneous catalysis</li><li>Scientists involved in catalyst development and characterization</li><li>Researchers working in CO₂ utilization, carbon management, and sustainable catalysis</li></ul><blockquote>Presenter: Md Monir Hossain, PhD Candidate, Michigan State UniversityResearcher focused on heterogeneous catalysis, carbon utilization, and DRIFTS studies of ceria-supported catalysts for dry reforming of methane.Presenter: Jim Delaney, Applications Team Lead, SpecacLeader of global spectroscopy application development and customer engagement efforts, supporting advanced research and industrial spectroscopy workflows.Presenter: Lena Woodis, PhD Product Manager, Thermo Fisher ScientificVibrational spectroscopy veteran with more than 15 years of experience in chemical instrumentation, FTIR spectroscopy, and analytical technologies.</blockquote>

Thermo Fisher Scientific: From Spectra to Mechanism: Using DRIFTS to Understand CO₂ Catalysis

From Spectra to Mechanism: Using DRIFTS to Understand CO₂ Catalysis

In this webinar, subject matter specialists will discuss how in situ DRIFTS can be used to study dry reforming of methane over ceria-supported catalysts.

Using DRIFTS to Understand CO₂ Catalysis

Food fraud, adulteration, and mislabeling continue to challenge global food supply chains, creating risks for manufacturers, regulators, retailers, and consumers. Stable isotope ratio mass spectrometry (IRMS) provides a powerful analytical approach for verifying food authenticity by measuring naturally occurring isotope fingerprints that reflect a product's origin, production practices, and ingredient composition.In this webinar, we will explore how isotope fingerprinting can be used to authenticate food and beverage products, detect economically motivated adulteration, and verify geographical origin claims. Attendees will gain an understanding of the scientific principles behind carbon, nitrogen, oxygen, hydrogen, and sulfur isotope analysis, along with the analytical technologies used to generate these fingerprints.<h4>Through practical case studies, we will demonstrate how isotope analysis can:</h4><ul><li>Detect honey adulteration with added sugar syrups using official AOAC methods.&nbsp;</li><li>Verify the geographical origin of beef through dietary isotope signatures.&nbsp;</li><li>Differentiate authentic and mislabeled coffee based on regional rainfall patterns.&nbsp;</li><li>Identify watering of wine and other beverage adulteration.&nbsp;</li><li>Confirm organic versus conventional agricultural practices.&nbsp;</li><li>Authenticate flavors, oils, sugars, and premium food products using multi-isotope approaches.</li></ul>Attendees will leave with a practical understanding of how isotope fingerprinting can be applied to real-world food integrity challenges, including origin verification, adulteration detection, and label claim validation. Through application-focused case studies and regulatory examples, participants will gain insights into selecting the appropriate isotope measurements and analytical workflows to strengthen food authenticity programs and combat food fraud across complex supply chains.<blockquote>Presenter: Christy Mancuso (Technical Sales Specialist, Thermo Fisher Scientific)Christy is an isotope ratio mass spectrometry (IRMS) specialist with experience in forensic science, food authenticity, and ecology. She earned her PhD at the University of Utah and completed postdoctoral research at the University of New Mexico. She joined Thermo Fisher Scientific in 2022 and supports IOMS sales in the Eastern US.</blockquote>

Thermo Fisher Scientific: Food Authenticity Uncovered - Using Isotope Fingerprints to Detect Adulteration and Verify Origin

Food Authenticity Uncovered: Using Isotope Fingerprints to Detect Adulteration and Verify Origin

Combat food fraud using Stable Isotope Ratio Mass Spectrometry (IRMS). Learn how isotope fingerprints verify origin and detect adulteration

Food Authenticity & Origin via Isotope Fingerprinting

Renewable energy resources such as solar are promising complements to the combustion of fossil fuels. However, the intermittent and diurnal nature of sunlight necessitates economical and efficient energy storage technologies. A promising approach to both storing solar energy and generating combustible liquid fuels is driving the transformation of abundant energy-poor feedstocks (CO2, H2O) into energy-dense liquid fuels using energy from solar photons, known as “artificial photosynthesis.”&nbsp;One approach for artificial photosynthesis is to immobilize fuel-producing molecular catalysts onto light-absorbing semiconductor materials to create “hybrid photoelectrodes,” allowing for both the stability of heterogenous surfaces and the tunability of molecular catalysts. The Center for Hybrid Approaches in Solar Energy to Liquid Fuels (CHASE) is a multi-institutional energy innovation hub which aims to advance hybrid photoelectrodes for the light-driven generation of liquid fuels from CO2 and H2O. A variety of chemical techniques, including sonochemical hydrosilylation, π-π stacking, and electrochemical grafting, are utilized to anchor ruthenium and rhenium molecular CO2-reduction catalysts to a silicon surface.&nbsp;To study the efficacy of these catalyst loading techniques, Inductively Coupled Plasma Mass Spectrometry (employing an Agilent 7850 ICP-MS) is leveraged to quantify catalyst surface coverage. Silicon samples are digested in an HNO3/HCl matrix to solubilize ruthenium and rhenium metal centers. As each anchored molecular catalyst contains one metal center, surface coverage estimates can be drawn by pairing ICP-MS data with the dimensions of the catalyst and the size of the silicon photoelectrode. From these data, key conclusions are drawn which correlate anchoring technique, reaction time, and silicon morphology to the loadings of these molecular catalysts. This information provides a guiding framework for next-generation designs of hybrid photoelectrodes.<blockquote>Presenter: Jillian L. Dempsey (Director, Center for Hybrid Approaches in Solar Energy to Liquid Fuels (CHASE) and an Associate Editor for ACS Electrochemistry)Jillian L. Dempsey is a professor at the University of North Carolina at Chapel Hill. She is currently the Director of the Center for Hybrid Approaches in Solar Energy to Liquid Fuels (CHASE) and an Associate Editor for ACS Electrochemistry.Jillian received her S.B. from the Massachusetts Institute of Technology in 2005 where she worked in the laboratory of Prof. Daniel G. Nocera. As an NSF Graduate Research Fellow, she carried out research with Prof. Harry B. Gray and Dr. Jay R. Winkler at the California Institute of Technology, receiving her PhD in 2011. From 2011–2012 she was an NSF ACC Postdoctoral Fellow with Daniel R. Gamelin at the University of Washington.In 2012, Jillian joined the faculty at the University of North Carolina at Chapel Hill. Her research group explores charge transfer processes associated with energy capture and conversion, including proton-coupled electron transfer reactions and electron transfer across interfaces. Her research bridges molecular and materials chemistry and relies heavily on methods of physical inorganic chemistry, including transient absorption spectroscopy and electrochemistry.She has received numerous awards including the Harry B. Gray Award for Creative Work in Inorganic Chemistry by a Young Investigator (2019), the J. Carlyle Sitterson Award for Teaching First-Year Students (2017), a Sloan Research Fellowship (2016), a Packard Fellowship for Science and Engineering (2015), the Agnes Fay Morgan Research Award (2020), the University Award for Advancement of Women (2021), and the Brown Investigator Award (2026).</blockquote><blockquote>Presenter: Rebecca E. Powers (Graduate Student, University of North Carolina at Chapel Hill)Rebecca (Becca) E. Powers is a fourth-year graduate student at the University of North Carolina at Chapel Hill in Prof. Jillian L. Dempsey’s research group.Becca graduated summa cum laude with a B.S. in Chemistry and B.S. in Physics from Creighton University in 2022. At Creighton University, she researched in the laboratories of Dr. Kayode Oshin and Dr. Janet Seger. While pursuing degrees in both chemistry and physics, Becca conducted research across both fields, including work on the Relativistic Heavy Ion Collider (RHIC) at Brookhaven National Laboratory. Becca was selected as both a Clare Boothe Luce fellow and a Goldwater Scholar during her undergraduate studies.Becca joined Prof. Jillian Dempsey’s lab in 2022 and began researching as a part of the Center for Hybrid Approaches in Solar Energy to Liquid Fuels (CHASE). Her research explores the chemical and physical properties of semiconducting photoelectrodes for photon capture and solar fuel generation. Becca’s research utilizes a large range of techniques, including electrochemistry, inductively coupled plasma-mass spectroscopy (ICP-MS), X-ray photoelectron spectroscopy (XPS), and time-resolved infrared spectroscopy (TRIR). Becca’s outreach and research efforts have been recognized with a Prof. James Tamage Dobbins Award and UNC Chemistry Graduate Student Award for Research Excellence.</blockquote>

Agilent Technologies: ICP-MS for Hybrid Photoelectrode Characterization

ICP-MS for Hybrid Photoelectrode Characterization

Learn how the Agilent 7850 ICP-MS quantifies catalyst surface coverage on hybrid photoelectrodes to advance artificial photosynthesis and solar fuel research

Hybrid Photoelectrode Characterization via ICP-MS

Laboratories are under growing pressure to handle increasing volumes of samples and data while operating under tighter regulatory inspection, all without compromising turnaround times or traceability. In this context, many organizations attempt to extend existing workflows and legacy tools, which can introduce inefficiencies, increase manual effort, and create compliance risks. At the same time, it is not always clear which digital solutions are best suited to address these challenges.This presentation illustrates how modern digital laboratory environments streamline routine activities by minimizing manual tasks and embedding compliance directly into everyday workflows. Drawing on a real-world use case, we show how automated capture of data from multiple sample measurements at the point of execution enables a continuous, sample-centric workflow.By removing manual interventions and paper-based processes, laboratories can improve efficiency and visibility, support faster and more reliable decision-making while remaining responsive to evolving customer demands.<h4>Learning Points</h4><ul><li>The role of different systems (LIMS, SDMS, ELN) within the digital lab landscape and how they differ from each other's</li><li>How WebLab manages laboratory operations from a sample perspective, enabling you to track every sample, stage, and next action across workflows</li><li>How automated data capture from connected instruments helps reduce errors, lower contamination risks, and accelerate sample processing</li><li>You will see, through a real-life example, how integrated digital workflows improve data quality, accelerate reporting, and increase operational efficiency</li></ul><h4>Who should attend</h4>Professionals working in small to mid‑sized laboratories, including:<ul><li>Directors and Managers of Analytical, QC, or Contract Labs</li><li>Lab Operations and QA/QC Leaders</li><li>Digitalization and IT at organizations transitioning from paper, Excel, or legacy systems to LIMS</li></ul><blockquote>Presenter: Peter Bellstedt, PhD (Director of Business Development and Product Manager at SciY)Peter studied Biochemistry at the University of Jena before completing a PhD on the structural characterization of a DNA repair protein using solution and solid-state NMR. He was then appointed as the head of the NMR Spectroscopy Platform in Jena, Germany, where he pioneered the implementation of modern, highly efficient data-driven workflows. After five years, he moved to the University of Zurich, Switzerland, as a principal investigator, where his lab focused on structure-based drug discovery. This year, he brought his wealth of experience to the LOGS by SciY team, focusing on efficient workflow solutions for research labs and facilities on a global scale.</blockquote>

SciY: From Legacy Workflows to Paperless Labs: Track Every Sample, Process, and Decision

From Legacy Workflows to Paperless Labs: Track Every Sample, Process, and Decision

Transition from paper to a paperless lab. Discover how WebLab, LIMS, and automated data capture streamline sample tracking and boost compliance

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